The recommended starting dosage for adults and children 6 years of age and older is 64 mcg per day administered as one spray per nostril of RHINOCORT AQUA (budesonide) Nasal Spray 32 mcg once daily. Some patients who do not achieve symptom control at the recommended starting dosage may benefit from an increased dosage. The maximum recommended dosage for adults (12 years of age and older) is 256 mcg per day administered as four sprays per nostril once daily of RHINOCORT AQUA (budesonide) Nasal Spray 32 mcg and the maximum recommended dose for pediatric patients (6 to < 12 years of age) is 128 mcg per day administered as two sprays per nostril once daily of RHINOCORT AQUA (budesonide) Nasal Spray 32 mcg. Speak to your doctor or pharmacist before you start using Rhinocort Aqua nasal spray if any of the following applies to you: Rhinocort aqua won't relieve your symptoms straight away - you have to use it regularly for a few days for it to build up an effect.

The recommended dose for adults is two sprays into each nostril in the morning. However, in some cases your doctor may instruct you to use one spray into each nostril each morning and evening. The safety and effectiveness of RHINOCORT AQUA (budesonide) Nasal Spray has not been shown in children under 6 years of age.Rhinocort and Flonase are both effective for relieving symptoms after exposure to allergens such as pollen, pet dander, and dust mites. However, Flonase may contain a stronger corticosteroid than Rhinocort. Different factors can affect the potency of a nasal spray, such as dosage and administration. While Flonase may be stronger, it may cause more side effects than Rhinocort. When should you not use Rhinocort? You may not notice any effects of the medicine for the first few days. Do not stop using this medicine. Keep taking the medicine as you have been told to. If your symptoms are not controlled after 14 days , talk to your doctor or pharmacist.

Patients previously treated for prolonged periods with systemic corticosteroids should be weaned off slowly when transferred to topical corticosteroids and carefully monitored for acute adrenal insufficiency in response to stressIf you have ever had a bad reaction to budesonide or any of the other ingredients of this medicine (listed in section 6). Insert the tip of the nasal spray's nozzle into your nostril, directing the nozzle to the side of your nose. Rhinocort is available as a nasal spray bottle that delivers 32 mcg of budesonide per spray. The usual dosage is one to two sprays into each nostril depending on the individual’s age. Rhinocort is not recommended in children under the age of 6. You must talk to a doctor if you do not feel better or if you feel worse after 14 days. How do you take Rhinocort?

Along with its needed effects, budesonide nasal (the active ingredient contained in Rhinocort Aqua) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. An improvement in nasal symptoms may be noted in patients within 10 hours of first using RHINOCORT AQUA (budesonide) Nasal Spray. This time to onset is supported by an environmental exposure unit study in seasonal allergic rhinitis patients that demonstrated that RHINOCORT AQUA (budesonide) Nasal Spray led to a statistically significant improvement in nasal symptoms compared to placebo by 10 hours. Further support comes from a clinical study of patients with perennial allergic rhinitis which demonstrated a statistically significant improvement in nasal symptoms for both RHINOCORT AQUA (budesonide) Nasal Spray and for the active comparator (mometasone furoate) compared to placebo by 8 hours. Onset was also assessed in this study with peak nasal inspiratory flow rate and this endpoint failed to show efficacy for either active treatment. Although statistically significant improvements in nasal symptoms compared to placebo were noted within 8-10 hours in these studies, about one half to two thirds of the ultimate clinical improvement with RHINOCORT AQUA (budesonide) Nasal Spray occurs over the first 1-2 days, and maximum benefit may not be achieved until approximately 2 weeks after initiation of treatment. assure optimal dose delivery [see PATIENT INFORMATION]. Nonclinical Toxicology Carcinogenesis, Mutagenesis, Impairment of Fertility Prime the nasal spray before your first use. Shake well and pump 8 test sprays into the air, away from your face. Pump the spray until a fine mist appears. Prime again whenever the inhaler has not been used in longer than 2 days, or if it has been dropped.

The systemic effects of inhaled corticosteroids are related to the systemic exposure to such drugs. Pharmacokinetic studies have demonstrated that in both adults and children, systemic exposure to budesonide at the highest recommended doses of RHINOCORT AQUA (budesonide) Nasal Spray would be expected to be no greater than exposure at the lowest recommended doses via a dry powder inhaler. Therefore, the systemic effects (HPA axis and growth) of budesonide delivered from RHINOCORT AQUA (budesonide) Nasal Spray would be expected to be no greater than what is reported for inhaled budesonide when administered via the dry powder inhaler. discontinue treatment with RHINOCORT AQUA (budesonide) Nasal spray. In addition, nasal corticosteroids This Patient Information leaflet summarizes the most important information about RHINOCORT AQUA (budesonide) Nasal Spray. If you would like more information, talk with your healthcare provider. You can ask your pharmacist or healthcare provider for information about RHINOCORT AQUA (budesonide) Nasal Spray that is written for health professionals. Because of the inhibitory effect of corticosteroids on wound healing, patients who have experienced recent nasal septal ulcers, nasal surgery, or nasal trauma should not use a nasal corticosteroid until healing has occurred. Hypersensitivity Reactions Including Anaphylaxis Patients should be advised that hypersensitivity reactions including anaphylactic reaction, urticaria, rash, dermatitis, angioedema and pruritus have been reported with use of RHINOCORT AQUA (budesonide) Nasal Spray. Discontinue